Organic Acids
Medchemexpress LLC ATX-II TFA | 99.7% | 4934.62 | 500 UG
ATX-II TFA is a selective sodium channel modulator toxin that enhances late sodium current, prevents full sodium channel inactivation, and generates persistent current fractions. It has a pro-arrhythmic effect, slowing intrinsic heart rate and prolonging QT interval. This compound is suitable for research on atrial fibrillation, long QT syndrome, and long QT3 syndrome.
Medchemexpress LLC Lagipra peptide (TFA) | 98.2% | 5756.50 (free base) | 1 MG
LAGIPRA peptide TFA is a long-acting GIP1R agonist. It enhances insulin sensitivity by augmenting glucose disposal and reduces branched-chain amino acids (BCAAs) and ketoacids. This peptide has potential for the research of type 2 diabetes.
- Long-acting GIP1R agonist
- Enhances insulin sensitivity
- Reduces branched-chain amino acids (BCAAs)
- Reduces ketoacids
- Potential for type 2 diabetes research
Medchemexpress LLC TP-5801 (TFA) | 99.6% | 641.48 | 100 MG
TP-5801 TFA is an orally active TNK1 (non-receptor tyrosine kinase) inhibitor with an IC50 of 1.40 nM, demonstrating anti-tumor activity. It inhibits TNK1-driven, BCR-ABL-driven, and IL-3-driven Ba/F3 cell growth, and TNK1-dependent L540 cell growth.
- Orally active
- Potent TNK1 inhibitor (IC50=1.40 nM)
- Demonstrates anti-tumor activity
- Inhibits growth of various cell lines (Ba/F3 and L540) relevant to TNK1-driven processes
- Shows efficacy in animal models, prolonging lifespan and inhibiting localized tumor growth without signs of toxicity
TARGETMOL CHEMICALS INC CYN 154806 TFA 1MG
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. CYN 154806 TFA is a cyclic octapeptide and an effective selective somatostatin sst2 receptor antagonist. For the recombinant sst2, sst1, sst3, sst4 and sst5 receptors, the pIC50 values are 8.58, 5.41, 6.07, 5.76 and 6.48, respectively. Purity 99.7%
Medchemexpress LLC PBX-7011 TFA | 98.6% | 561.46 | 25 MG
PBX-7011 TFA is a derivative of camptothecin that exhibits anticancer activity. It functions by inhibiting the expression of cancer-related survival genes, specifically DDX5, Survivin, Mcl-1, and XIAP, in FaDu cells. Additionally, it degrades DDX5 proteins.
- Derivative of camptothecin.
- Inhibits expressions of cancer related survival genes DDX5, Survivin, Mcl-1, and XIAP in FaDu cells.
- Degrades DDX5 proteins.
- Exhibits anticancer activity.
